Apcgenereview

由 B Kim 著作 · 2019 · 被引用 24 次 — Next-generation sequencing with comprehensive bioinformatics analysis facilitates somatic mosaic APC gene mutation detection in patients with ...

The APC is a tumour suppressor gene responsible for the production of adenomatous polyposis coli (APC), a large multifunction tumour-suppressing protein which ...

由 BA Talseth-Palmer 著作 · 2017 · 被引用 110 次 — APC is a tumour suppressor gene that plays a central role in the Wnt signalling pathway. A detailed review of APC structure and function has ...

A person who fulfils criteria for polyposis panel testing; A person with an intra-abdominal or abdominal wall desmoid tumour over age 10 years ...

由 R Fodde 著作 · 2001 · 被引用 1189 次 — The APC gene is regarded as the gene for colorectal cancer as it is found mutated in most sporadic cases regardless of the histological stage. APC encodes a ...

由 S Carr 著作 · 2023 · 被引用 32 次 — The APC gene functions as a tumor suppressor gene and plays a vital role in the alignment of chromosomes during metaphase. The normal APC protein promoted ...

由 T Yen 著作 · 2022 · 被引用 205 次 — APC-associated polyposis conditions include (classic or attenuated) familial adenomatous polyposis (FAP) and gastric adenocarcinoma and proximal polyposis of ...

由 AS Aghabozorgi 著作 · 2019 · 被引用 116 次 — This review summarizes the roles of somatic and germline mutations of the APC gene in hereditary as well as sporadic forms of CRC. We also discuss the ...

由 M Pang 著作 · 2018 · 被引用 7 次 — A novel APC mutation identified in a large Chinese family with familial adenomatous polyposis and a brief literature review. Authors:.